Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4yao2AMNADPH--cytochrome P450 reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4yao2AMNADPH--cytochrome P450 reductase/1.000
4yaw2AMNADPH--cytochrome P450 reductase/0.637
4y7cNAPNADPH--cytochrome P450 reductase/0.631
4yal2AMNADPH--cytochrome P450 reductase/0.616
1amoNAPNADPH--cytochrome P450 reductase/0.615
4y9uNAPNADPH--cytochrome P450 reductase/0.615
4y9rNAPNADPH--cytochrome P450 reductase/0.601
4yau2AMNADPH--cytochrome P450 reductase/0.601
4yaf2AMNADPH--cytochrome P450 reductase/0.562
3qfsNAPNADPH--cytochrome P450 reductase/0.534
3qfcNAPNADPH--cytochrome P450 reductase/0.516
3qfrNAPNADPH--cytochrome P450 reductase/0.510
3qe2NAPNADPH--cytochrome P450 reductase/0.501
2bpoNAPNADPH--cytochrome P450 reductase/0.492
2bf4NAPNADPH--cytochrome P450 reductase/0.485
1je1GMPPurine nucleoside phosphorylase/0.483
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.479
1ja1NAPNADPH--cytochrome P450 reductase/0.478
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.467
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.463
1vbmYSATyrosine--tRNA ligase6.1.1.10.462
3ojxNAPNADPH--cytochrome P450 reductase/0.456
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.455
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.455
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.455
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
4xwtU5PRibonuclease J/0.454
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.453
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.451
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.451
3t4eNADQuinate/shikimate dehydrogenase/0.450
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.448
2ed3SAHDiphthine synthase/0.448
2oxnOANBeta-hexosaminidase/0.448
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.448
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
3rbaCODPhosphopantetheine adenylyltransferase/0.446
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
4fhf0TTSpore photoproduct lyase/0.443
4j7hTRHPCZA361.3/0.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.442
2bn4NAPNADPH--cytochrome P450 reductase/0.441
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
1c7oPPGHemolysin/0.440
4bfzZVZPantothenate kinase2.7.1.330.440