sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4wbn | GTP | Tubulin alpha-1B chain |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4wbn | GTP | Tubulin alpha-1B chain | / | 1.000 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.825 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.767 | |
| 4tuy | GTP | Tubulin alpha-1B chain | / | 0.715 | |
| 5la6 | GTP | Tubulin alpha-1B chain | / | 0.700 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.653 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.623 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.603 | |
| 3ryh | GTP | Tubulin alpha chain | / | 0.597 | |
| 4iij | GTP | Tubulin alpha-1B chain | / | 0.595 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.580 | |
| 4ffb | GTP | Tubulin alpha-1 chain | / | 0.565 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.540 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.503 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.489 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.482 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.476 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.473 | |
| 2o12 | FMN | Chorismate synthase | / | 0.462 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.459 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.456 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.454 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.453 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.452 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 5la6 | GDP | Tubulin beta-2B chain | / | 0.448 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.446 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.445 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.441 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2x3j | ATP | AcsD | / | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 |