Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4pl8ATPActin, alpha skeletal muscle

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4pl8ATPActin, alpha skeletal muscle/1.000
1t44ATPActin, alpha skeletal muscle/0.646
4k41ATPActin, alpha skeletal muscle/0.644
1lotATPActin, alpha skeletal muscle/0.640
1s22ATPActin, alpha skeletal muscle/0.625
4k42ADPActin, alpha skeletal muscle/0.625
2q36ATPActin, alpha skeletal muscle/0.619
4pkgATPActin, alpha skeletal muscle/0.611
3m6gATPActin, alpha skeletal muscle/0.609
1h1vATPActin, alpha skeletal muscle/0.606
3ffkATPActin, alpha skeletal muscle/0.606
1c0fATPMajor actin/0.605
1rgiATPActin, alpha skeletal muscle/0.605
1qz5ATPActin, alpha skeletal muscle/0.604
3tu5ATPActin, alpha skeletal muscle/0.603
4ci6ATPActin/0.595
4pkhADPActin, alpha skeletal muscle/0.592
5ce3ATPActin/0.592
3mn6ATPActin-5C/0.591
2q97ATPActin, alpha skeletal muscle/0.587
1nm1ATPMajor actin/0.583
2v51ATPActin, alpha skeletal muscle/0.582
3u9dATPActin, alpha skeletal muscle/0.579
4m63ATPActin-5C/0.570
3a5mATPMajor actin/0.569
1eqyATPActin, alpha skeletal muscle/0.567
4jhdANPActin-5C/0.567
1nmdATPMajor actin/0.563
1yxqATPActin, alpha skeletal muscle/0.559
2p9kATPActin-related protein 2/0.557
1ijjATPActin, alpha skeletal muscle/0.552
3m1fATPActin, alpha skeletal muscle/0.551
3mn7ATPActin-5C/0.550
3el2ATPActin-5C/0.549
3dawATPActin, alpha skeletal muscle/0.545
4rwtANPActin-5C/0.544
3mn9ATPActin-5C/0.543
1kxpATPActin, alpha skeletal muscle/0.541
3eksATPActin-5C/0.538
4k43ADPActin, alpha skeletal muscle/0.533
4cbxATPActin-2/0.526
3u4lATPActin, cytoplasmic 1/0.525
3chwATPMajor actin/0.517
1mduATPActin, alpha skeletal muscle/0.515
2oanATPActin, cytoplasmic 1/0.507
4pkiATPActin, alpha skeletal muscle/0.505
1dejATPMajor actin/0.504
3w3dATPActin, gamma-enteric smooth muscle/0.504
2a41ATPActin, alpha skeletal muscle/0.495
1wuaATPActin, alpha skeletal muscle/0.494
3a5oATPMajor actin/0.477
3ekuATPActin-5C/0.470
1nlvATPMajor actin/0.449
3uleATPActin-related protein 2/0.447