sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4oad | CLM | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4oad | CLM | Uncharacterized protein | / | 1.000 | |
| 4oae | CLM | Uncharacterized protein | / | 0.742 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.593 | |
| 4kub | COA | Uncharacterized protein | / | 0.568 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.481 | |
| 3f8k | COA | Uncharacterized protein | / | 0.480 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.475 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.474 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.470 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.466 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 4jxr | ACO | Acetyltransferase | / | 0.459 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.458 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.457 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.457 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.455 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.455 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.455 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.454 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 5ftf | ADP | TPR domain protein | / | 0.452 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.451 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.448 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.447 | |
| 4cpd | NAD | Alcohol dehydrogenase | / | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.441 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.441 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.440 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.440 |