sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nb6 | 444 | Nuclear receptor ROR-gamma |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 1.000 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.544 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.523 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.496 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.477 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.476 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.463 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.460 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.455 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.447 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.446 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.446 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.443 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3lu8 | IQX | Serum albumin | / | 0.440 |