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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4lol1YEStimulator of interferon genes protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4lol1YEStimulator of interferon genes protein/1.000
4qxp1YEStimulator of interferon genes protein/0.535
4jc51K5Stimulator of interferon genes protein/0.533
4qxr1YEStimulator of interferon genes protein/0.532
4qxq1YEStimulator of interferon genes protein/0.484
4loi1YCStimulator of interferon genes protein/0.461
5cfpC2EStimulator of interferon genes protein/0.461
1f8fNADBenzyl alcohol dehydrogenase/0.457
3tjzGNPADP-ribosylation factor 1/0.456
1icqFMN12-oxophytodienoate reductase 11.3.1.420.455
1lbcCYZGlutamate receptor 2/0.449
2dftADPShikimate kinase2.7.1.710.448
3lpjZ75Beta-secretase 13.4.23.460.448
3qt62P0Mevalonate diphosphate decarboxylase/0.448
4df2FMNNADPH dehydrogenase/0.448
2oapANPType II secretion system protein (GspE-2)/0.447
1udaUFGUDP-glucose 4-epimerase5.1.3.20.446
1xe55FEPlasmepsin-23.4.23.390.446
3gw9VNILanosterol 14-alpha-demethylase/0.446
1kp3ATPArgininosuccinate synthase6.3.4.50.444
3cid318Beta-secretase 13.4.23.460.442
3lqfNADGalactitol dehydrogenase/0.442
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.441
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.441
4h1vGNPDynamin-1-like protein3.6.5.50.440