scPDB - Distribution of Binding site Similarity values of 4l2k entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4l2k	1V8	Tankyrase-2	2.4.2.30

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4l2k	1V8	Tankyrase-2	2.4.2.30	1.000
4l0s	1UZ	Tankyrase-2	2.4.2.30	0.685
4bux	F35	Tankyrase-2	2.4.2.30	0.683
4l34	1VG	Tankyrase-2	2.4.2.30	0.678
4l0t	1V0	Tankyrase-2	2.4.2.30	0.672
4bud	29F	Tankyrase-2	2.4.2.30	0.671
4j22	AJ7	Tankyrase-2	2.4.2.30	0.671
4l2g	1V4	Tankyrase-2	2.4.2.30	0.666
4l31	F08	Tankyrase-2	2.4.2.30	0.666
4buf	F36	Tankyrase-2	2.4.2.30	0.665
4kzu	A73	Tankyrase-2	2.4.2.30	0.665
4bue	JQF	Tankyrase-2	2.4.2.30	0.664
4bu9	08C	Tankyrase-2	2.4.2.30	0.662
4buu	F38	Tankyrase-2	2.4.2.30	0.660
4l0i	1UW	Tankyrase-2	2.4.2.30	0.660
4hlf	15Z	Tankyrase-2	2.4.2.30	0.656
4avw	G18	Tankyrase-2	2.4.2.30	0.654
4hkk	AGI	Tankyrase-2	2.4.2.30	0.654
5aku	29F	Tankyrase-2	2.4.2.30	0.654
4iue	AJ4	Tankyrase-2	2.4.2.30	0.651
4l0v	1V1	Tankyrase-2	2.4.2.30	0.651
4l33	F70	Tankyrase-2	2.4.2.30	0.651
4hl5	15W	Tankyrase-2	2.4.2.30	0.648
4hlk	431	Tankyrase-2	2.4.2.30	0.647
4l2f	1V3	Tankyrase-2	2.4.2.30	0.641
4but	31F	Tankyrase-2	2.4.2.30	0.637
4l32	1VF	Tankyrase-2	2.4.2.30	0.637
4l10	A63	Tankyrase-2	2.4.2.30	0.636
4bui	W2E	Tankyrase-2	2.4.2.30	0.635
3kr8	XAV	Tankyrase-2	2.4.2.30	0.632
4kzl	20D	Tankyrase-2	2.4.2.30	0.631
4hkn	LU2	Tankyrase-2	2.4.2.30	0.628
4hlm	16S	Tankyrase-2	2.4.2.30	0.625
4bus	32F	Tankyrase-2	2.4.2.30	0.622
4hlg	20B	Tankyrase-2	2.4.2.30	0.616
4j21	AJ6	Tankyrase-2	2.4.2.30	0.616
4bs4	A64	Tankyrase-2	2.4.2.30	0.608
4hki	FLN	Tankyrase-2	2.4.2.30	0.607
4hmh	F94	Tankyrase-2	2.4.2.30	0.600
4buw	F33	Tankyrase-2	2.4.2.30	0.591
3p0p	NNF	Tankyrase-2	2.4.2.30	0.589
4bj9	UHB	Tankyrase-2	2.4.2.30	0.586
4hlh	20D	Tankyrase-2	2.4.2.30	0.585
4krs	1SX	Tankyrase-1	2.4.2.30	0.563
4tkg	09L	Tankyrase-2	2.4.2.30	0.559
3u9y	09L	Tankyrase-2	2.4.2.30	0.557
4pnr	G18	Tankyrase-2	2.4.2.30	0.550
4buv	16I	Tankyrase-2	2.4.2.30	0.533
4avu	LDR	Tankyrase-2	2.4.2.30	0.529
4j3m	AJ8	Tankyrase-2	2.4.2.30	0.526
4bjb	P34	Tankyrase-2	2.4.2.30	0.523
4l09	1UR	Tankyrase-2	2.4.2.30	0.512
4j3l	AJ5	Tankyrase-2	2.4.2.30	0.506
4pnm	NU1	Tankyrase-2	2.4.2.30	0.502
4tjy	3GN	Tankyrase-2	2.4.2.30	0.490
4msk	2C8	Tankyrase-1	2.4.2.30	0.470
3h4v	DVP	Pteridine reductase 1	1.5.1.33	0.463
2bf7	HBI	Pteridine reductase 1	1.5.1.33	0.462
2bfa	CB3	Pteridine reductase 1	1.5.1.33	0.461
3jyn	NDP	Quinone oxidoreductase	/	0.456
3gn7	3GN	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.452
4mm7	29J	Na(+):neurotransmitter symporter (Snf family)	/	0.447
2p8u	COA	Hydroxymethylglutaryl-CoA synthase, cytoplasmic	2.3.3.10	0.444
3a25	SAM	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase	/	0.441
1amo	FMN	NADPH--cytochrome P450 reductase	/	0.440