scPDB - Distribution of Binding site Similarity values of 4ktt entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ktt	SAM	S-adenosylmethionine synthase isoform type-2	2.5.1.6

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4ktt	SAM	S-adenosylmethionine synthase isoform type-2	2.5.1.6	1.000
4ndn	SAM	S-adenosylmethionine synthase isoform type-2	2.5.1.6	0.582
1rg9	SAM	S-adenosylmethionine synthase	2.5.1.6	0.575
4l2z	S7M	S-adenosylmethionine synthase	/	0.475
4ug9	1EW	Nitric oxide synthase oxygenase	1.14.13.165	0.456
1e6e	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.455
1rek	B8L	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.453
2olc	ADP	Methylthioribose kinase	2.7.1.100	0.448
4ug5	XFK	Nitric oxide synthase oxygenase	1.14.13.165	0.447