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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4igeCHJEnoyl-acyl carrier reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4igeCHJEnoyl-acyl carrier reductase/1.000
3lt1FT2Enoyl-ACP reductase/0.561
1nnuTCTEnoyl-ACP reductase/0.552
3lt0FT1Enoyl-ACP reductase/0.551
3lt2FT3Enoyl-ACP reductase/0.550
3am3TCLEnoyl-ACP reductase/0.540
3lsyFT0Enoyl-ACP reductase/0.525
3nj8NJ8Enoyl-acyl carrier reductase/0.513
2ol4JPNEnoyl-ACP reductase/0.507
3am4FT1Enoyl-ACP reductase/0.505
2op07PCEnoyl-ACP reductase/0.491
1uh5TCLEnoyl-ACP reductase/0.487
1zsnTN2Enoyl-ACP reductase/0.487
1zw1TN5Enoyl-ACP reductase/0.484
1nhgTCLEnoyl-ACP reductase/0.483
1zxlJP1Enoyl-ACP reductase/0.483
2o2yTCLEnoyl-ACP reductase/0.475
3f4bTCLEnoyl-acyl carrier protein reductase/0.475
2foiJPAEnoyl-acyl carrier reductase/0.470
1nhwTCCEnoyl-ACP reductase/0.467
2o2sTCLEnoyl-acyl carrier reductase/0.464
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
3am5TCLEnoyl-ACP reductase/0.453
3p4tFAOPutative acyl-CoA dehydrogenase/0.449
3k4nFADPyranose 2-oxidase/0.440