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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.581.000
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.596
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.559
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.525
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.511
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.509
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.509
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.497
1s63778Protein farnesyltransferase subunit beta2.5.1.580.495
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.493
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.485
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.480
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.476
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.463
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.456
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.442