Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gevCB3Thymidylate synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gevCB3Thymidylate synthase/1.000
2ftoCB3Thymidylate synthase/0.626
4knzCB3Thymidylate synthase/0.602
3bgxMEFThymidylate synthase/0.590
1tysDHFThymidylate synthase/0.552
4isk1JYThymidylate synthase/0.551
1tduCB3Thymidylate synthase/0.536
1fwmCB3Thymidylate synthase/0.528
3bhlTHGThymidylate synthase/0.527
3bhrTHGThymidylate synthase/0.527
1f4fTP3Thymidylate synthase/0.524
4fogC2FThymidylate synthase ThyA/0.504
1dduCB3Thymidylate synthase/0.500
4ez8DHFThymidylate synthase2.1.1.450.499
1f4gTP4Thymidylate synthase/0.487
4o7uTHFThymidylate synthase/0.484
4fqsLYAThymidylate synthase ThyA/0.472
1an5CB3Thymidylate synthase/0.465
1tlcF89Thymidylate synthase/0.454