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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ejmNAPPutative zinc-binding dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ejmNAPPutative zinc-binding dehydrogenase/1.000
1tehNADAlcohol dehydrogenase class-31.1.1.10.510
4gl4NAIAlcohol dehydrogenase class-3/0.505
4jjiNADAlcohol dehydrogenase class-3/0.495
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.486
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.482
3gw9VNILanosterol 14-alpha-demethylase/0.478
1f8fNADBenzyl alcohol dehydrogenase/0.470
2ejvNADL-threonine 3-dehydrogenase/0.469
2fzwNADAlcohol dehydrogenase class-31.1.1.10.469
2vwqNAPGlucose 1-dehydrogenase/0.463
3gfbNADL-threonine 3-dehydrogenase/0.463
1e3eNAIAlcohol dehydrogenase 41.1.1.10.459
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.450
1mp0NADAlcohol dehydrogenase class-31.1.1.10.447
2xaaNADSecondary alcohol dehydrogenase/0.447
2dfvNADL-threonine 3-dehydrogenase/0.445
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.444
1cdoNADAlcohol dehydrogenase 11.1.1.10.441
2iko7IGRenin3.4.23.150.441
2ikuLIYRenin3.4.23.150.441