Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4e5nNADPhosphonate dehydrogenase1.20.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4e5nNADPhosphonate dehydrogenase1.20.1.11.000
4nu5NADPhosphonate dehydrogenase1.20.1.10.591
4nu6NADPhosphonate dehydrogenase1.20.1.10.551
4e5kNADPhosphonate dehydrogenase1.20.1.10.547
4e5mNAPPhosphonate dehydrogenase1.20.1.10.539
2dbzNAPGlyoxylate reductase1.1.1.260.527
2w2lNADD-mandelate dehydrogenase/0.487
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.477
3bazNAPHydroxyphenylpyruvate reductase1.1.1.2370.474
2dbqNAPGlyoxylate reductase1.1.1.260.473
1g4tFTPThiamine-phosphate synthase/0.470
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
5j23A2RPutative 2-hydroxyacid dehydrogenase/0.467
4weqNAPNAD-dependent dehydrogenase/0.465
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.464
4z0pNDPNAD-dependent dehydrogenase/0.464
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.460
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1hkuNADC-terminal-binding protein 11.1.10.455
5bqfNAPProbable hydroxyacid dehydrogenase protein/0.455
4i6gFADCryptochrome-2/0.453
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.452
2tpsTPSThiamine-phosphate synthase/0.451
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
3kb6NADD-lactate dehydrogenase/0.450
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.448
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.447
1g67TZPThiamine-phosphate synthase/0.446
3t2zFADSulfide-quinone reductase/0.446
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.446
2eklNADD-3-phosphoglycerate dehydrogenase/0.445
3a1l2CCCytochrome P450/0.445
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.445
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
4mo2FADUDP-galactopyranose mutase/0.443
2y05NAPProstaglandin reductase 1/0.442
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.442
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.441
3u4cNDPNADPH-dependent reductase BacG/0.441
3vt65YIVitamin D3 receptor/0.441
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.441
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.440