sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 | / | 1.000 | |
| 4ozn | ATP | Ammonium transporter | / | 0.543 | |
| 3ncq | ATP | Nitrogen regulatory protein P-II (GlnB-2) | / | 0.540 | |
| 1v3s | ATP | Signaling protein | / | 0.539 | |
| 2xzw | ATP | Nitrogen regulatory protein P-II | / | 0.529 | |
| 3ncr | ADP | Nitrogen regulatory protein P-II (GlnB-2) | / | 0.513 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.511 | |
| 3ta0 | ATP | Nitrogen regulatory protein P-II (GlnB-3) | / | 0.507 | |
| 3mhy | ATP | Nitrogen regulatory protein P-II 1 | / | 0.504 | |
| 1v9o | ADP | Signaling protein | / | 0.491 | |
| 2xul | ATP | Nitrogen regulatory protein P-II | / | 0.482 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.477 | |
| 3ta1 | ADP | Nitrogen regulatory protein P-II (GlnB-3) | / | 0.474 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.473 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.466 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.459 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.458 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.456 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.456 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.456 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.453 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.452 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.452 | |
| 2bun | FAD | AppA protein | / | 0.450 | |
| 1qy8 | RDI | Endoplasmin | / | 0.449 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1sny | NAP | LD36273p | / | 0.448 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.446 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.444 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.443 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.442 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.441 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.440 |