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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4buiW2ETankyrase-22.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4buiW2ETankyrase-22.4.2.301.000
4buuF38Tankyrase-22.4.2.300.756
4but31FTankyrase-22.4.2.300.752
5aku29FTankyrase-22.4.2.300.738
4hlk431Tankyrase-22.4.2.300.734
4bu908CTankyrase-22.4.2.300.709
4l0s1UZTankyrase-22.4.2.300.708
4bufF36Tankyrase-22.4.2.300.696
4kzl20DTankyrase-22.4.2.300.653
4avwG18Tankyrase-22.4.2.300.644
4l2f1V3Tankyrase-22.4.2.300.643
4hkiFLNTankyrase-22.4.2.300.642
3kr8XAVTankyrase-22.4.2.300.620
4l0i1UWTankyrase-22.4.2.300.617
4l10A63Tankyrase-22.4.2.300.606
4l31F08Tankyrase-22.4.2.300.606
4bueJQFTankyrase-22.4.2.300.603
4kzuA73Tankyrase-22.4.2.300.603
4l0v1V1Tankyrase-22.4.2.300.601
4hlg20BTankyrase-22.4.2.300.600
4l341VGTankyrase-22.4.2.300.595
4l321VFTankyrase-22.4.2.300.593
4buv16ITankyrase-22.4.2.300.592
4buxF35Tankyrase-22.4.2.300.585
4l0t1V0Tankyrase-22.4.2.300.585
4bus32FTankyrase-22.4.2.300.582
4l33F70Tankyrase-22.4.2.300.581
4hlh20DTankyrase-22.4.2.300.580
4l2g1V4Tankyrase-22.4.2.300.577
4l2k1V8Tankyrase-22.4.2.300.573
4hl515WTankyrase-22.4.2.300.562
4hlf15ZTankyrase-22.4.2.300.562
4bud29FTankyrase-22.4.2.300.560
4hkkAGITankyrase-22.4.2.300.557
4hknLU2Tankyrase-22.4.2.300.552
4iueAJ4Tankyrase-22.4.2.300.550
4j21AJ6Tankyrase-22.4.2.300.543
4j22AJ7Tankyrase-22.4.2.300.535
4l091URTankyrase-22.4.2.300.532
4hlm16STankyrase-22.4.2.300.527
3p0pNNFTankyrase-22.4.2.300.519
4buwF33Tankyrase-22.4.2.300.519
4bs4A64Tankyrase-22.4.2.300.515
4hmhF94Tankyrase-22.4.2.300.506
4bj9UHBTankyrase-22.4.2.300.488
4krs1SXTankyrase-12.4.2.300.482
4tkg09LTankyrase-22.4.2.300.482
4pnrG18Tankyrase-22.4.2.300.470
4bjbP34Tankyrase-22.4.2.300.465
4j3mAJ8Tankyrase-22.4.2.300.451
4j3lAJ5Tankyrase-22.4.2.300.449
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.443
4pnmNU1Tankyrase-22.4.2.300.442
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.440