sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b0i | KBP | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4b0i | KBP | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 1.000 | |
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.655 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.490 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.463 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.457 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.455 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.450 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 4b0j | 3MQ | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.448 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.447 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.446 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.445 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.444 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.442 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.442 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.442 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.442 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1w87 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.440 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 |