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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.620
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.616
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.615
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.594
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.590
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.590
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.590
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.589
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.502
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.467
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.463
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.454
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.450
4qnyANPMitogen activated protein kinase, putative/0.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.445
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.444
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441