sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rha | FDA | Putrescine oxidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rha | FDA | Putrescine oxidase | / | 1.000 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.577 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.524 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.512 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.506 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.504 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.495 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.493 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.491 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.490 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.489 | |
| 2bab | FAD | Putative aminooxidase | / | 0.481 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.478 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.478 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.473 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.472 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.466 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.464 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.463 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.461 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.460 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.458 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.456 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.451 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.451 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.450 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.448 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.447 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.447 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.446 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.441 |