sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qji | MGP | Ribosome inactivating protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qji | MGP | Ribosome inactivating protein | / | 1.000 | |
| 4emr | MGP | Ribosome inactivating protein | / | 0.674 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.666 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.660 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.612 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.598 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.537 | |
| 4zz6 | CTP | Ribosome inactivating protein | / | 0.527 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.462 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.454 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.447 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.446 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.446 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.443 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.442 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.441 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.440 |