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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3qa2XNAKetohexokinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3qa2XNAKetohexokinase/1.000
3q92XNBKetohexokinase/0.733
3qaiXNNKetohexokinase/0.660
3nc9TR3Ketohexokinase/0.651
3nbvANPKetohexokinase/0.618
2hw1ANPKetohexokinase/0.610
3nbwTR4Ketohexokinase/0.564
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.452
1gqtACPRibokinase/0.446
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446