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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o8hO8HHTH-type transcriptional regulator EthR

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3o8hO8HHTH-type transcriptional regulator EthR/1.000
3g1mRF3HTH-type transcriptional regulator EthR/0.654
3q0uLL3HTH-type transcriptional regulator EthR/0.654
3o8gO8GHTH-type transcriptional regulator EthR/0.642
3sfi3SFHTH-type transcriptional regulator EthR/0.637
3tp0FO5HTH-type transcriptional regulator EthR/0.632
3q0vLL4HTH-type transcriptional regulator EthR/0.622
4dw60MNHTH-type transcriptional regulator EthR/0.506
3g1lRF2HTH-type transcriptional regulator EthR/0.476
1yqxNAPSinapyl alcohol dehydrogenase/0.457
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.457
5dbgNADIridoid synthase1.3.1.990.452
2y6fM9FIsopenicillin N synthase1.21.3.10.448
2vbpVB1Isopenicillin N synthase1.21.3.10.447
3g1oRF1HTH-type transcriptional regulator EthR/0.444
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.443
4yryFADGlutamate synthase, beta subunit/0.443
4phlPILPhosphodiesterase/0.441
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.440
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
3ol5SAWCamphor 5-monooxygenase1.14.15.10.440