Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o3rNAPAldose reductase-related protein 11.1.1.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3o3rNAPAldose reductase-related protein 11.1.1.211.000
2j8tNAPAldose reductase1.1.1.210.540
2iq0NAPAldose reductase1.1.1.210.534
1x96NAPAldose reductase1.1.1.210.530
1x98NAPAldose reductase1.1.1.210.524
2acqNAPAldose reductase1.1.1.210.523
3q67NAPAldose reductase1.1.1.210.522
3v36NAPAldose reductase1.1.1.210.519
2acsNAPAldose reductase1.1.1.210.514
3q65NAPAldose reductase1.1.1.210.514
2pf8NDPAldose reductase1.1.1.210.509
1z8aNAPAldose reductase1.1.1.210.502
2pfhNDPAldose reductase1.1.1.210.497
1az2NAPAldose reductase1.1.1.210.492
1ah4NAPAldose reductase1.1.1.210.491
1s1rNAPAldo-keto reductase family 1 member C3/0.489
2acuNAPAldose reductase1.1.1.210.489
2pevNDPAldose reductase1.1.1.210.489
4jtqNAPAldo-keto reductase family 1 member C2/0.489
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.487
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.481
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.480
1adsNAPAldose reductase1.1.1.210.476
2hdjNDPAldo-keto reductase family 1 member C2/0.475
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.467
4dz5NAPAldo-keto reductase family 1 member C3/0.466
4xo7NAPAldo-keto reductase family 1 member C2/0.465
1c9wNAPAldose reductase-related protein 2/0.461
3h7rNAPAldo-keto reductase family 4 member C8/0.457
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.453
3qkzNAPAldose reductase-related protein 11.1.1.210.450
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.447
3wczNAPAldo-keto reductase AKR2E4/0.445
2hejNDPAldo-keto reductase family 1 member C211.1.10.443
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
4jq3NAPAldo-keto reductase family 1 member C2/0.440