sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mzi | FMN | Activator of photopigment and puc expression |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3mzi | FMN | Activator of photopigment and puc expression | / | 1.000 | |
| 2hfo | FMN | Activator of photopigment and puc expression | / | 0.518 | |
| 2hfn | FMN | Activator of photopigment and puc expression | / | 0.513 | |
| 1x0p | FAD | Tll0078 protein | / | 0.498 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.466 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.465 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.457 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.456 | |
| 4hh0 | FMN | AppA protein | / | 0.456 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.454 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.453 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.452 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.450 | |
| 2c4g | 514 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2r4f | RIE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.447 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.447 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3gg1 | FMN | Uncharacterized protein | / | 0.446 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4uux | APR | CinA-like protein | / | 0.440 |