Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3mdeCO8Medium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3mdeCO8Medium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.71.000
1egcCO8Medium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.561
1ivhCOSIsovaleryl-CoA dehydrogenase, mitochondrial1.3.8.40.488
4l1fCOSAcyl-CoA dehydrogenase domain protein/0.474
1jqiCAAShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.460
1rx02MCIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.460
2w98P1ZProstaglandin reductase 21.3.1.480.447
2ix5CAAAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.445
3mpiGRAGlutaryl-CoA dehydrogenase1.3.99.320.442