sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lbe | COA | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3lbe | COA | Uncharacterized protein | / | 1.000 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.471 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.462 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.461 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.460 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.458 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.456 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.456 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.456 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 5a3b | APR | SIR2 family protein | / | 0.455 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.452 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.452 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.451 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.448 | |
| 2x92 | X92 | Angiotensin-converting enzyme | 3.4.15.1 | 0.447 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.447 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.447 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.446 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.446 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.446 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.444 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.444 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.443 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.441 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.441 | |
| 7req | 2CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.440 |