sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kpb | SAM | Uncharacterized protein MJ0100 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 1.000 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.481 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.479 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.474 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.456 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.453 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.451 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.451 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.443 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.443 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.442 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.442 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.440 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 |