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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ictFADCoenzyme A disulfide reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ictFADCoenzyme A disulfide reductase/1.000
3icsFADCoenzyme A disulfide reductase/0.569
4ocgFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.565
3icrFADCoenzyme A disulfide reductase/0.537
3ntaFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.533
3ntdFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.515
2eq9FADDihydrolipoyl dehydrogenase/0.472
3cgbFADCoenzyme A disulfide reductase/0.471
4eqwFADCoenzyme A disulfide reductase/0.451
3cgcFADCoenzyme A disulfide reductase/0.450
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.450
2eq6FADDihydrolipoyl dehydrogenase/0.447
3nt6FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.442
3r9uFADThioredoxin reductase/0.441
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.440
4eqsFADCoenzyme A disulfide reductase/0.440
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440