Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3h24B55Dihydropteroate synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3h24B55Dihydropteroate synthase/1.000
3h2cB58Dihydropteroate synthase/0.611
3tydXHPDihydropteroate synthase/0.600
3tycXHPDihydropteroate synthase/0.565
3h23B54Dihydropteroate synthase/0.560
3h2nB62Dihydropteroate synthase/0.536
2dzbHH2Dihydropteroate synthase/0.528
2y5s78HDihydropteroate synthase/0.500
3issEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.479
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.475
2vnjNAPNADPH:ferredoxin reductase/0.466
1n1eNDEGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.462
1twwHH2Dihydropteroate synthase/0.458
4xouACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.458
4cx5H4BNitric oxide synthase, brain1.14.13.390.457
3h4vNAPPteridine reductase 11.5.1.330.456
1aj22PHDihydropteroate synthase/0.454
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.453
2cbsR13Cellular retinoic acid-binding protein 2/0.452
4loh1SYStimulator of interferon genes protein/0.452
3aw9GDUNAD-dependent epimerase/dehydratase/0.451
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
1z0sATPNAD kinase/0.448
2gn4UD1UDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.447
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3qiyQI1Botulinum neurotoxin type A3.4.24.690.446
3ea0ATPATPase, ParA family/0.444
2xpwOTCTetracycline repressor protein class D/0.443
5aglH4BNitric oxide synthase, brain1.14.13.390.443
1dliUDXUDP-glucose 6-dehydrogenase/0.442
1mdlRMNMandelate racemase/0.442
3svqH4BNitric oxide synthase, brain1.14.13.390.442
4jsfH4BNitric oxide synthase, brain1.14.13.390.442
1wg8SAMRibosomal RNA small subunit methyltransferase H/0.441
4fqfNADAldehyde dehydrogenase, mitochondrial1.2.1.30.440