sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3h06 | VBP | Glutamate receptor 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3h06 | VBP | Glutamate receptor 2 | / | 1.000 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.597 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.584 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.521 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.483 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.477 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.463 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 5a3c | NAD | SIR2 family protein | / | 0.456 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.455 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.453 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.453 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.452 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.451 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.451 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.450 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.449 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 5dp2 | NAP | CurF | / | 0.449 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.447 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.445 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.444 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.443 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.441 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.441 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 4die | C5P | Cytidylate kinase | / | 0.440 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.440 |