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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3gn2AX8Pteridine reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3gn2AX8Pteridine reductase/1.000
2wd8VGFPteridine reductase/0.639
3jqbDX6Pteridine reductase, putative/0.512
3jq6DX1Pteridine reductase, putative/0.504
3jq7DX2Pteridine reductase, putative/0.504
3jqgAX6Pteridine reductase, putative/0.496
3bmqAX5Pteridine reductase/0.489
3jq9AX1Pteridine reductase, putative/0.468
3jq8DX3Pteridine reductase, putative/0.463
2aouCQAHistamine N-methyltransferase2.1.1.80.460
2vz0D64Pteridine reductase/0.458
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2x9vTMQPteridine reductase/0.442