Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.21.000
2j0lANPFocal adhesion kinase 12.7.10.20.509
2ijmATPFocal adhesion kinase 12.7.10.20.464
4j99ACPFibroblast growth factor receptor 2/0.458
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.457
4j95ACPFibroblast growth factor receptor 2/0.454
2ijmADPFocal adhesion kinase 12.7.10.20.453
5dosATPAurora kinase A2.7.11.10.452
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.451
3bu5ATPInsulin receptor2.7.10.10.449
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.449
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.446
4ysjADPCalmodulin-like domain protein kinase/0.446
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.444
4l9i8PRRhodopsin kinase/0.444
4qmlANPSerine/threonine-protein kinase 242.7.11.10.444
2v7a627Tyrosine-protein kinase ABL12.7.10.20.441