Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3erkSB4Mitogen-activated protein kinase 12.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3erkSB4Mitogen-activated protein kinase 12.7.11.241.000
4fuxE75Mitogen-activated protein kinase 12.7.11.240.519
1tvoFRZMitogen-activated protein kinase 12.7.11.240.515
4id71G0Activated CDC42 kinase 1/0.495
2c6eHPMAurora kinase A2.7.11.10.488
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.488
4fv9E71Mitogen-activated protein kinase 12.7.11.240.478
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.475
2ghmLICMitogen-activated protein kinase 14/0.471
3vjoANPEpidermal growth factor receptor2.7.10.10.470
2yxuATPPyridoxal kinase2.7.1.350.465
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.465
3keuATPPyridoxal kinase2.7.1.350.462
2ojj82AMitogen-activated protein kinase 12.7.11.240.459
4ix5ANPUncharacterized protein/0.459
4en4ATPPyridoxal kinase2.7.1.350.458
3d8vUD1Bifunctional protein GlmU/0.457
2xvdAS6Ephrin type-B receptor 42.7.10.10.456
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.456
4s33ANPMitogen-activated protein kinase 12.7.11.240.455
3w32W32Epidermal growth factor receptor2.7.10.10.453
3fhyATPPyridoxal kinase2.7.1.350.452
3ztxZTXAurora kinase B-A2.7.11.10.452
4b99R4LMitogen-activated protein kinase 72.7.11.240.452
4gt3ATPMitogen-activated protein kinase 12.7.11.240.451
4s34ANPMitogen-activated protein kinase 12.7.11.240.450
2qoqANPEphrin type-A receptor 32.7.10.10.448
5l8lADPAurora kinase A2.7.11.10.448
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.446
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.446
4c4g7RODual specificity protein kinase TTK2.7.12.10.445
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.444
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.444
4f9wLM4Mitogen-activated protein kinase 14/0.444
3gc9B45Mitogen-activated protein kinase 112.7.11.240.443
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.442
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.442
3flsFLSMitogen-activated protein kinase 14/0.440