sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3d2m | COA | Amino-acid acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3d2m | COA | Amino-acid acetyltransferase | / | 1.000 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.628 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.564 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.473 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.472 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.469 | |
| 1s7n | COA | Acetyl transferase | / | 0.466 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.465 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.463 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.462 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.462 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.459 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.458 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.457 | |
| 4psw | COA | Histone acetyltransferase type B catalytic subunit | / | 0.456 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.454 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.453 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.450 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3r95 | ACO | MccE protein | / | 0.448 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.448 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 4c4o | NAD | SADH | / | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.447 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.444 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.443 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.441 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.441 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.441 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.440 |