sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 1.000 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.544 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.497 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.481 | |
| 3c1o | NAP | Eugenol synthase | / | 0.472 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.443 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.441 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 |