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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2zreAGSProtein RecA

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2zreAGSProtein RecA/1.000
2zrfDTPProtein RecA/0.600
2zrjAGSProtein RecA/0.576
2zroADPProtein RecA/0.568
1xp8AGSProtein RecA/0.557
2zr9DTPProtein RecA/0.524
1xmvADPProtein RecA/0.501
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.457
4b65FADL-ornithine N(5)-monooxygenase/0.456
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
2g226IGRenin3.4.23.150.450
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4j0v1H7Beta-secretase 13.4.23.460.448
2dvlFADAcyl-CoA dehydrogenase/0.447
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.447
2g247IGRenin3.4.23.150.446
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.445
1bim0QBRenin3.4.23.150.444
5dp2NAPCurF/0.444
2ikuLIYRenin3.4.23.150.443
2bf4FMNNADPH--cytochrome P450 reductase/0.441
2webPP4Penicillopepsin-13.4.23.200.441
4bfxZVXPantothenate kinase2.7.1.330.441
3cb2GDPTubulin gamma-1 chain/0.440
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4dieC5PCytidylate kinase/0.440