sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2znq | 401 | Peroxisome proliferator-activated receptor delta |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 1.000 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.616 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.591 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.584 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.577 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.570 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.569 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.563 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.540 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.520 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.518 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.518 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.516 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.516 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.514 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.513 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.513 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.501 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.499 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.497 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.497 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.497 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.491 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.491 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.489 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.482 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.481 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.481 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.476 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.463 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.441 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 |