Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2yutNAPPutative short-chain oxidoreductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2yutNAPPutative short-chain oxidoreductase/1.000
4j7xNAPSepiapterin reductase1.1.1.1530.518
4hwkNAPSepiapterin reductase1.1.1.1530.505
1xg5NAPDehydrogenase/reductase SDR family member 11/0.500
1xkqNDPUncharacterized protein/0.497
1n5dNDPCarbonyl reductase [NADPH] 1/0.495
4j7uNAPSepiapterin reductase1.1.1.1530.493
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.492
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.492
4bmvNAPShort-chain dehydrogenase/0.490
1oaaNAPSepiapterin reductase1.1.1.1530.488
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.482
1x7gNAPPutative ketoacyl reductase1.3.10.478
3ai2NDPNADPH-sorbose reductase/0.477
4pvdNDPNADPH-dependent methylglyoxal reductase GRE2/0.475
1ae1NAPTropinone reductase 1/0.473
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.473
1w4zNAPPutative ketoacyl reductase1.3.10.471
4qecNAPElxO/0.470
1ipeNDPTropinone reductase 21.1.1.2360.465
5jlaNADPutative short-chain dehydrogenase/reductase/0.463
1snyNAPLD36273p/0.462
3p19NDPPutative blue fluorescent protein/0.461
3gy0NAPNAD(P)-dependent oxidoreductase/0.460
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.460
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3l77NJPShort-chain alcohol dehydrogenase/0.459
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4impNDPPolyketide synthase extender modules 3-4/0.458
4dc1NDPPutative ketoacyl reductase1.3.10.457
2jahNDPClavaldehyde dehydrogenase/0.456
2bd0NAPSepiapterin reductase/0.455
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.454
5idwNAPShort-chain dehydrogenase/reductase SDR/0.454
3ai3NDPNADPH-sorbose reductase/0.453
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.452
3qrwNDPPutative ketoacyl reductase1.3.10.451
1g6kNADGlucose 1-dehydrogenase1.1.1.470.448
1x7hNDPPutative ketoacyl reductase1.3.10.447
3toxNAPPutative oxidoreductase/0.446
4jbiNDPAlcohol dehydrogenase (Zinc)/0.446
4qedNAPElxO/0.443
1pr9NAPL-xylulose reductase1.1.1.100.441
3uceNDPDehydrogenase/0.441
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.440