Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.11.000
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.680
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.647
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.643
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.638
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.631
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.623
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.609
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.600
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.573
4jbpYPHAurora kinase A2.7.11.10.535
4jboWPHAurora kinase A2.7.11.10.505
1jklANPDeath-associated protein kinase 12.7.11.10.487
2vrx447Aurora kinase B-A2.7.11.10.476
3w2sW2REpidermal growth factor receptor2.7.10.10.475
2c6eHPMAurora kinase A2.7.11.10.473
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.462
3bu5ATPInsulin receptor2.7.10.10.460
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.460
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.458
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.456
3vs1VSATyrosine-protein kinase HCK2.7.10.20.456
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.455
4ysjADPCalmodulin-like domain protein kinase/0.455
3gu7ADPDeath-associated protein kinase 12.7.11.10.454
1ig1ANPDeath-associated protein kinase 12.7.11.10.453
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.452
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.451
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.451
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.449
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.448
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.446
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.445
5av2KMPDeath-associated protein kinase 12.7.11.10.444
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.443
4jbqVX6Aurora kinase A2.7.11.10.443
4iaq2GM5-hydroxytryptamine receptor 1B/0.442
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.440
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.440