scPDB - Distribution of Binding site Similarity values of 2xug entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2xug	TZ4	Acetylcholinesterase	3.1.1.7

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2xug	TZ4	Acetylcholinesterase	3.1.1.7	1.000
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.793
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.659
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.645
2xuq	TZ4	Acetylcholinesterase	3.1.1.7	0.631
1q83	TZ5	Acetylcholinesterase	3.1.1.7	0.574
2xuk	TZ5	Acetylcholinesterase	3.1.1.7	0.572
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.556
2gyw	OBI	Acetylcholinesterase	3.1.1.7	0.535
2jf0	HBP	Acetylcholinesterase	3.1.1.7	0.527
2ckm	AA7	Acetylcholinesterase	3.1.1.7	0.511
2gyu	HI6	Acetylcholinesterase	3.1.1.7	0.495
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.495
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.490
4ara	C56	Acetylcholinesterase	3.1.1.7	0.485
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.481
4arb	C57	Acetylcholinesterase	3.1.1.7	0.480
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.472
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.471
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.470
2wu4	HBP	Acetylcholinesterase	3.1.1.7	0.469
2xui	TZ5	Acetylcholinesterase	3.1.1.7	0.466
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.458
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.455
4b7z	Q4Q	Acetylcholinesterase	3.1.1.7	0.453
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.449
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.445