sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2x7c | KZ9 | Kinesin-like protein KIF11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2x7c | KZ9 | Kinesin-like protein KIF11 | / | 1.000 | |
| 1x88 | NAT | Kinesin-like protein KIF11 | / | 0.678 | |
| 3k5e | K5E | Kinesin-like protein KIF11 | / | 0.665 | |
| 2x7d | EGB | Kinesin-like protein KIF11 | / | 0.624 | |
| 2ieh | MOY | Kinesin-like protein KIF11 | / | 0.614 | |
| 1q0b | NAT | Kinesin-like protein KIF11 | / | 0.593 | |
| 2x7e | X7E | Kinesin-like protein KIF11 | / | 0.574 | |
| 2q2z | MKK | Kinesin-like protein KIF11 | / | 0.566 | |
| 2xae | 2XA | Kinesin-like protein KIF11 | / | 0.565 | |
| 2fme | 3QC | Kinesin-like protein KIF11 | / | 0.562 | |
| 3ken | ZZD | Kinesin-like protein KIF11 | / | 0.557 | |
| 4bbg | V02 | Kinesin-like protein KIF11 | / | 0.545 | |
| 2g1q | N9H | Kinesin-like protein KIF11 | / | 0.542 | |
| 3k3b | L31 | Kinesin-like protein KIF11 | / | 0.533 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.530 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.529 | |
| 2wog | ZZD | Kinesin-like protein KIF11 | / | 0.527 | |
| 2gm1 | 2AZ | Kinesin-like protein KIF11 | / | 0.488 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.470 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.454 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.452 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.452 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 2q54 | MU1 | Protease | / | 0.448 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.446 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.446 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.444 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.442 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3so9 | 017 | Pol protein | / | 0.442 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.441 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.440 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 |