Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2w4jADPDeath-associated protein kinase 12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2w4jADPDeath-associated protein kinase 12.7.11.11.000
1ig1ANPDeath-associated protein kinase 12.7.11.10.762
1jkkANPDeath-associated protein kinase 12.7.11.10.599
1jklANPDeath-associated protein kinase 12.7.11.10.597
3gu7ADPDeath-associated protein kinase 12.7.11.10.551
4ysjADPCalmodulin-like domain protein kinase/0.547
4qnyANPMitogen activated protein kinase, putative/0.527
5dnrATPAurora kinase A2.7.11.10.498
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.495
5dosATPAurora kinase A2.7.11.10.492
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.485
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.484
1qmzATPCyclin-dependent kinase 22.7.11.220.478
1dayGNPCasein kinase II subunit alpha2.7.11.10.476
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.472
2cjmATPCyclin-dependent kinase 22.7.11.220.471
2yaaATPDeath-associated protein kinase 2/0.470
5av2KMPDeath-associated protein kinase 12.7.11.10.467
4deeADPAurora kinase A2.7.11.10.462
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.461
3zxtACPDeath-associated protein kinase 12.7.11.10.460
5cvfATPCasein kinase II subunit alpha2.7.11.10.459
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.458
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.457
5av3KMPDeath-associated protein kinase 12.7.11.10.456
4eooATPCyclin-dependent kinase 22.7.11.220.453
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.451
3c4zADPRhodopsin kinase/0.451
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.451
3orpAGSSerine/threonine protein kinase/0.447
4s33ANPMitogen-activated protein kinase 12.7.11.240.447
3c4wATPRhodopsin kinase/0.444
5ap7SVEDual specificity protein kinase TTK2.7.12.10.444
4xlvACPInsulin receptor2.7.10.10.443
2ijmATPFocal adhesion kinase 12.7.10.20.442
3i60E86Mitogen-activated protein kinase 12.7.11.240.442
4jboWPHAurora kinase A2.7.11.10.442