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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2v18FMNDodecin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2v18FMNDodecin/1.000
2vyxFMNDodecin/0.687
2v19FMNDodecin/0.551
1e79ATPATP synthase subunit alpha, mitochondrial/0.460
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.460
2vbdV10Isopenicillin N synthase1.21.3.10.455
4bfxZVXPantothenate kinase2.7.1.330.454
2bu9HFVIsopenicillin N synthase1.21.3.10.450
1qiqACCIsopenicillin N synthase1.21.3.10.447
2vbpVB1Isopenicillin N synthase1.21.3.10.446
4a8v2ANMajor pollen allergen Bet v 1-J/0.446
2uxoTACHTH-type transcriptional regulator TtgR/0.445
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
4tmcFMNOld yellow enzyme/0.445
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
1bwlFMNNADPH dehydrogenase 11.6.99.10.441
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.441
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.441
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3rupADPBiotin carboxylase6.3.4.140.440