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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2tmdADPTrimethylamine dehydrogenase1.5.8.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2tmdADPTrimethylamine dehydrogenase1.5.8.21.000
1djqADPTrimethylamine dehydrogenase1.5.8.20.826
1djnADPTrimethylamine dehydrogenase1.5.8.20.749
1o94ADPTrimethylamine dehydrogenase1.5.8.20.572
1u7hNADPutative ornithine cyclodeaminase/0.468
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.460
4b69FADL-ornithine N(5)-monooxygenase/0.453
4bk3FADProbable salicylate monooxygenase/0.452
4opiFDAConserved Archaeal protein/0.452
4dbzNDPPutative ketoacyl reductase1.3.10.449
1w4xFADPhenylacetone monooxygenase1.14.13.920.448
3cgeFADCoenzyme A disulfide reductase/0.448
3fpzAHZThiamine thiazole synthase/0.445
3f8rNAPNADH oxidase/thioredoxin reductase/0.442
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.441
2zzcFADThioredoxin reductase 1, cytoplasmic1.8.1.90.441
4tm4FDAKtzI/0.440