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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2q9fC3SCholesterol 24-hydroxylase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2q9fC3SCholesterol 24-hydroxylase/1.000
3mdvCL6Cholesterol 24-hydroxylase/0.517
4enhFVXCholesterol 24-hydroxylase/0.496
4g3jVNTLanosterol 14-alpha-demethylase/0.474
3mdmFJZCholesterol 24-hydroxylase/0.464
4g7gVFVLanosterol 14-alpha-demethylase/0.447
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.445
3gw9VNILanosterol 14-alpha-demethylase/0.442