sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.859 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.703 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.677 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.669 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.669 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.662 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.661 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.657 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.657 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.652 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.652 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.645 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.645 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.643 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.638 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.638 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.635 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.634 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.633 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.632 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.631 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.629 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.626 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.621 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.619 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.613 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.609 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.608 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.608 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.601 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.600 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.599 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.599 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.597 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.591 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.590 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.583 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.582 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.576 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.574 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.571 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.566 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.565 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.565 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.564 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.542 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.541 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.527 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.513 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.503 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.502 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.502 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.498 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.496 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.496 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.496 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.495 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.494 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.492 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.490 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.490 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.488 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.487 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.487 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.483 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.479 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.479 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.479 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.479 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.474 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.474 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.473 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.473 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.472 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.471 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.471 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.471 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.471 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.470 | |
| 2qry | TPS | Thiamine-binding periplasmic protein | / | 0.470 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.470 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.469 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.469 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.469 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.468 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 4phl | PIL | Phosphodiesterase | / | 0.468 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.467 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.467 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.467 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.465 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.465 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.465 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.465 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.464 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.463 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.463 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.463 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.463 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.462 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.462 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.462 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.462 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.462 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.462 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.462 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.461 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.461 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.461 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.461 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.461 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4kmz | FOL | Folate receptor beta | / | 0.461 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.460 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.459 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.459 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.459 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.458 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.458 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.458 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.457 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.456 | |
| 1s36 | CEI | Obelin | / | 0.456 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.456 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.456 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.456 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.456 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.455 | |
| 1rxj | BNI | Streptavidin | / | 0.455 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.455 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.455 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.454 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.454 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.454 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.454 | |
| 4yfy | 0FX | VioF | / | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.453 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.453 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.452 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.452 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.452 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.451 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.451 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.451 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.450 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.450 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3af2 | ACP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4iae | 1DX | Alr2278 protein | / | 0.450 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.450 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4e2z | JHZ | Methyltransferase | / | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.449 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.449 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.449 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.448 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4e32 | DWN | Methyltransferase | / | 0.448 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4msk | 2C8 | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 1lke | DOG | Bilin-binding protein | / | 0.447 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.447 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.447 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.447 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.447 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.447 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.447 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.447 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.447 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 1dtp | APU | Diphtheria toxin | / | 0.446 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.446 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.445 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.445 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.445 | |
| 3pn1 | IVH | DNA ligase | / | 0.445 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.445 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 4j7h | TRH | PCZA361.3 | / | 0.445 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.445 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.445 | |
| 1jf2 | CZH | Obelin | / | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.444 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.443 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.443 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.443 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.443 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.443 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.443 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.443 | |
| 4kxj | P34 | Nucleoprotein | / | 0.443 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.443 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.442 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.442 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.442 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4mrx | CZH | Obelin | / | 0.442 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.442 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.441 | |
| 1w29 | TS1 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.441 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2hzq | STR | Apolipoprotein D | / | 0.441 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2oym | MNI | Endoglycoceramidase II | / | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.441 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.441 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.441 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.441 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.441 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 1uhj | CZB | Aequorin-2 | / | 0.440 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.440 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.440 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.440 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.440 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.440 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.440 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.440 |