sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jey | HLO | Acetylcholinesterase | 3.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2jey | HLO | Acetylcholinesterase | 3.1.1.7 | 1.000 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.566 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.501 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.461 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.452 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 1uhh | CZP | Aequorin-2 | / | 0.450 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.442 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 |