sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jap | J01 | Clavaldehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2jap | J01 | Clavaldehyde dehydrogenase | / | 1.000 | |
| 1fdo | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.478 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.476 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.470 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.462 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.454 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.452 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2ylw | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3mpi | GRA | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 1fdi | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4l9q | 9TP | Serum albumin | / | 0.449 | |
| 4ww9 | ADP | EKC/KEOPS complex subunit BUD32 | 3.6 | 0.449 | |
| 5eom | CTP | Putative nucleotidyltransferase MAB21L1 | / | 0.449 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.449 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.448 | |
| 1i7l | ATP | Synapsin-2 | / | 0.447 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.447 | |
| 3sop | GDP | Neuronal-specific septin-3 | / | 0.446 | |
| 1yp4 | ADP | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.445 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.444 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.444 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.442 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.442 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 5cku | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 5cns | CDP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.442 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.440 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.440 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.440 |