Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.79

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.791.000
2iskFNR5,6-dimethylbenzimidazole synthase1.13.11.790.581
2islFNR5,6-dimethylbenzimidazole synthase1.13.11.790.574
3e39FMNNitroreductase/0.499
3eo8FMNPutative nitroreductase/0.492
2ifaFMNUncharacterized protein/0.467
1kqdFMNOxygen-insensitive NAD(P)H nitroreductase/0.462
3pxvFMNNitroreductase/0.457
4a5lNDPThioredoxin reductase/0.455
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.453
2freFMNNAD(P)H-flavin oxidoreductase/0.452
3koqFMNPutative nitroreductase/0.451
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.451
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.450
1oonFMNOxygen-insensitive NAD(P)H nitroreductase/0.448
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.447
3lpgZ78Beta-glucuronidase3.2.1.310.445
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.442
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.441
2dr3ADPUPF0273 protein PH0284/0.440