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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2idxATPCob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial2.5.1.17

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2idxATPCob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial2.5.1.171.000
4zo3C6LAcylhomoserine lactonase/0.481
3q9aH4BNitric oxide synthase, brain1.14.13.390.464
4cx4H4BNitric oxide synthase, brain1.14.13.390.455
3tylH4BNitric oxide synthase, brain1.14.13.390.452
4uz6SCRPalmitoleoyl-protein carboxylesterase NOTUM/0.451
2getCOKPantothenate kinase2.7.1.330.443
4qak2AMRNA 2',3'-cyclic phosphodiesterase/0.442
5agkH4BNitric oxide synthase, brain1.14.13.390.442
5aglH4BNitric oxide synthase, brain1.14.13.390.441