scPDB - Distribution of Binding site Similarity values of 2fah entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2fah	GDP	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial	4.1.1.32

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2fah	GDP	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial	4.1.1.32	1.000
3dt2	GTP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.601
3dt4	GTP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.588
2qf2	GDP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.576
1khb	GCP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.466
1khe	GCP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.465
2q7o	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.461
3moh	GDP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.460
4ara	C56	Acetylcholinesterase	3.1.1.7	0.456
1amo	FMN	NADPH--cytochrome P450 reductase	/	0.452
4b4v	L34	Bifunctional protein FolD	/	0.452
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.451
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.450
2pid	YSA	Tyrosine--tRNA ligase, mitochondrial	6.1.1.1	0.444
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.444
4frk	DWD	Beta-secretase 1	3.4.23.46	0.443